Epidural Fever: Why a Fever Can Show Up After an Epidural
A mild fever during labor with an epidural is common and usually inflammation, not infection. Here's why it happens and why baby may get extra checks.
Thomas Lambert, MD··4 min read
If you spike a low fever during labor after getting an epidural, it can be unsettling — especially if your team starts talking about checking your baby for infection. Here's the reassuring short version: a mild rise in temperature is a fairly well-recognized thing that can happen with an epidural, it's usually not a sign that you have an infection, and the extra attention your baby may get is precaution, not alarm. Let me explain what's actually going on.
What "epidural fever" is
Researchers have noticed for years that some moms who use an epidural for labor develop a mild fever that they probably wouldn't have had otherwise. It's common enough to have a name in the medical literature: epidural-related maternal fever.
The honest truth is that the exact mechanism isn't fully settled. The leading explanation is that it's a form of non-infectious inflammation — your body's inflammatory system becoming a little more active during a long labor, reflected in higher levels of inflammatory signals (researchers often point to a marker called interleukin-6). Changes in how your body regulates temperature with an epidural in place may play a part too. The key word is non-infectious: in most cases, this fever is not because germs have taken hold.
Why it tends to happen with longer labors
Epidural-related fever is more likely the longer the epidural is in place, which is why it shows up more in longer labors. That's part of why it's hard to separate from the epidural itself — the moms who use epidurals the longest are often the ones in the most drawn-out labors.
It's worth saying clearly: this is not a reason to avoid an epidural. The temperature rise is usually modest, your team is watching for it, and the benefits of good pain relief in a long labor are real. It's simply one of the trade-offs worth understanding ahead of time so it doesn't catch you off guard.
Why your baby might get extra checks
Here's the part that worries moms most. The problem your care team faces is this: a fever in labor can be a sign of an infection in the womb (such as a uterine infection), and from the outside, an epidural-related fever and an infection fever can look similar. Because an infection that reaches the baby is something nobody wants to miss, the team errs on the side of caution.
In practice, that can mean a few things: monitoring you and your baby a little more closely, sometimes starting antibiotics for you as a precaution, and after birth, your baby's team may run some extra checks or observe your newborn for signs of infection. This can feel like a big deal in the moment. But it's important to understand the logic: they're not reacting because they're sure something is wrong — they're being thorough because fever is hard to interpret with certainty, and caution costs little.
What this means for you
A few things to hold onto if this happens:
A mild fever after an epidural is common and usually reflects inflammation, not infection.
Your team will likely treat it cautiously anyway, because they can't always tell the two apart in the moment — and caution is the safe choice.
Extra monitoring or precautionary antibiotics for you, or extra checks for your baby, are routine responses, not signs of a crisis.
It typically settles after birth, once the epidural is no longer in place.
If you spike a temperature during labor, you don't need to do anything except let your team lead — they're already watching for exactly this. And if it would help to talk through your particular situation beforehand, this is a great thing to raise at a conversation with your anesthesia team. Knowing the fever is a known, mostly benign phenomenon — and that the precautions around it are about thoroughness, not danger — is usually enough to take the fear out of the moment.
This content is general educational information about pregnancy, birth, and obstetric anesthesia. It is not medical advice and does not replace a conversation with your own doctor. Every birth is different. Talk to your healthcare team about what's right for your specific situation.
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Thomas Lambert, MD - Board-certified OB anesthesiologist writing an evergreen library for moms who want clear answers before delivery day.